BROLIN -S ORAL POWDER is a combination of three antibiotics with Bromhexine.
Lincomycine: Lincomycine is a lincosamide antibiotic that is produced by Streptomyces lincolnensis. It inhibits protein synthesis in susceptible bacteria by binding to the 50 S subunits of bacterial ribosomes and preventing peptide bond formation upon transcription.
Spectinomycine: Spectinomycin is an aminocyclitol antibiotic, which shares similar features with an aminoglycoside. Spectinomycin, like aminoglycosides, inhibits protein synthesis via a 30S ribosomal target. It is a broad spectrum drug with activity against gram-positive and some gram-negative bacteria and Mycoplasma.
Spiramycine: Macrolides like spiramycine are generally bacteriostatic, although some of these drugs may be bactericidal at very high concentrations (Anne Brisson-Noël et al., 1988). Spiramycin, a 16-membered macrolide, inhibits translocation by binding to bacterial 50S ribosomal subunits.
Bromhexine: Bromhexine is intended to support the body’s mechanisms for clearing mucus from the respiratory tract. It is mucolytic, increasing the production of serous mucus in the respiratory tract, which makes the phlegm thinner and less viscous. This contributes to a secretomotoric effect, allowing the cilia to more easily transport the phlegm out of the lungs.
Each KG contains
Lincomycin HCl.................50gm
Spectinomycin HCl..................75gm
Spiramycin Adipate .................25gm
Bromhexine HCl .................05gm
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